Year : 2020  |  Volume : 23  |  Issue : 1  |  Page : 43--47

Role of urinary PO2 analysis during conventional versus conventional and modified ultrafiltration techniques in adult cardiac surgery


Vijitha Burra1, PK Sunil2, NB Praveen1, PS Nagaraja1, Naveen G Singh1, N Manjunatha3, Vikram Somashekhar Basappanavar4 
1 Department of Anaesthesiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Jayanagar, Bengaluru, Karnataka, India
2 Department of Cardiovascular and Thoracic Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Jayanagar, Bengaluru, Karnataka, India
3 Department of Cardiac Anaesthesiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Jayanagar, Bengaluru, Karnataka, India
4 Department of Anesthesiology, Pediatric Cardiac Anesthesiologist, Al Jalila Childrens Hospital, Dubai, UAE

Correspondence Address:
P K Sunil
Department of Cardiovascular and Thoracic Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru - 560 069, Karnataka
India

Background: Medullary hypoxia is the initial critical event for kidney injury during cardiopulmonary bypass, and therefore urinary PO2 with its potential of detecting medullary oxygenation for its management. Therefore, we tested the role of urinary PO2 in predicting kidney injury in those undergoing conventional versus combined (conventional and modified) ultrafiltration during cardiac surgery in adults. Methodology: We prospectively evaluated 32 adults between 18 and 65 years of age undergoing elective on-pump cardiac surgery with ejection fraction >35% by conventional (group C) versus combined ultrafiltration (group CM). Urine samples were analyzed for PO2 after induction, 30 min, 3 h, and 6 h post filtration along with blood urea and serum creatinine after induction, at 6 h, 24 h, and 48 h post filtration. Demographic variables, cardiopulmonary bypass duration, flow rates, inotropic score, ventilation duration, diuretic use, and intensive care unit (ICU) stay were assessed between two groups. Results: Both the groups (16 in each group) had comparable urinary PO2 after induction (= 0.387) with significant decrease in group C at 30 min, 3 h, and 6 h post filtration (P < 0.05). There was a statistically significant increase in serum creatinine (mg/dL) at 48 h in group C compared with group CM (1.57 vs. 1.25, respectively; P ≤ 0.05). There was an increased diuretic usage and length of ICU stay in group C. Conclusion: Combined ultrafiltration technique had renoprotective effect in cardiac surgery analyzed by urinary PO2 levels.


How to cite this article:
Burra V, Sunil P K, Praveen N B, Nagaraja P S, Singh NG, Manjunatha N, Basappanavar VS. Role of urinary PO2 analysis during conventional versus conventional and modified ultrafiltration techniques in adult cardiac surgery.Ann Card Anaesth 2020;23:43-47


How to cite this URL:
Burra V, Sunil P K, Praveen N B, Nagaraja P S, Singh NG, Manjunatha N, Basappanavar VS. Role of urinary PO2 analysis during conventional versus conventional and modified ultrafiltration techniques in adult cardiac surgery. Ann Card Anaesth [serial online] 2020 [cited 2022 Jan 23 ];23:43-47
Available from: https://www.annals.in/article.asp?issn=0971-9784;year=2020;volume=23;issue=1;spage=43;epage=47;aulast=Burra;type=0