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ORIGINAL ARTICLE

Early goal-directed therapy in moderate to high-risk cardiac surgery patients

Kapoor Poonam Malhotra, Kakani Madhava, Chowdhury Ujjwal, Choudhury Minati, Lakshmy R, Kiran Usha

Year : 2008| Volume: 11| Issue : 1 | Page no: 27-34

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Pediatric Critical Care Medicine. 2016; 17: S207
[Pubmed]  [Google Scholar] [DOI]
2 A systematic review of pulse pressure variation and stroke volume variation to predict fluid responsiveness during cardiac and thoracic surgery
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3 The Use of Internal Jugular Vein Ultrasonography to Anticipate Low or High Central Venous Pressure During Mechanical Ventilation
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The Journal of Emergency Medicine. 2016;
[Pubmed]  [Google Scholar] [DOI]
4 Goal-directed therapy in the operating room
Jason B. O’Neal,Andrew D. Shaw
Current Opinion in Anaesthesiology. 2016; 29(1): 80
[Pubmed]  [Google Scholar] [DOI]
5 Fluid Status Assessment and Management during the Perioperative Phase in Adult Cardiac Surgery Patients
Stefano Romagnoli,Alessandra Rizza,Zaccaria Ricci
Journal of Cardiothoracic and Vascular Anesthesia. 2015;
[Pubmed]  [Google Scholar] [DOI]
6 A Randomised feasibility study to assess a novel strategy to rationalise fluid in patients after cardiac surgery
R L. Parke,S. P. McGuinness,E. Gilder,L. W. McCarthy,K.-A. L. Cowdrey,H. C. Hemmings
British Journal of Anaesthesia. 2015; 115(1): 45
[Pubmed]  [Google Scholar] [DOI]
7 Using cardiac output monitoring to guide perioperative haemodynamic therapy
Shay McGuinness,Rachael Parke
Current Opinion in Critical Care. 2015; 21(4): 364
[Pubmed]  [Google Scholar] [DOI]
8 Perioperative fluid theory: a statement from the international Fluid Optimization Group
Lais Helena Camacho Navarro,Joshua A Bloomstone,Jose Otavio Costa Auler,Maxime Cannesson,Giorgio Della Rocca,Tong J Gan,Michael Kinsky,Sheldon Magder,Timothy E Miller,Monty Mythen,Azriel Perel,Daniel A Reuter,Michael R Pinsky,George C Kramer
Perioperative Medicine. 2015; 4(1)
[Pubmed]  [Google Scholar] [DOI]
9 Goal-Directed Resuscitation Aiming Cardiac Index Masks Residual Hypovolemia: An Animal Experiment
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BioMed Research International. 2015; 2015: 1
[Pubmed]  [Google Scholar] [DOI]
10 Efficacy of Goal-Directed Therapy Using Bioreactance Cardiac Output Monitoring after Valvular Heart Surgery
Sak Lee,Seung Hyun Lee,Byung-Chul Chang,Jae-Kwang Shim
Yonsei Medical Journal. 2015; 56(4): 913
[Pubmed]  [Google Scholar] [DOI]
11 Systematic review of uncalibrated arterial pressure waveform analysis to determine cardiac output and stroke volume variation
C. Slagt,I. Malagon,A. B. J. Groeneveld
British Journal of Anaesthesia. 2014;
[Pubmed]  [Google Scholar] [DOI]
12 Cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis
N. Arulkumaran,C. Corredor,M. A. Hamilton,J. Ball,R. M. Grounds,A. Rhodes,M. Cecconi
British Journal of Anaesthesia. 2014;
[Pubmed]  [Google Scholar] [DOI]
13 Fluid management in the cardiothoracic intensive care unit
Giovanni Mariscalco,Francesco Musumeci
Current Opinion in Anaesthesiology. 2014; 27(2): 133
[Pubmed]  [Google Scholar] [DOI]
14 The effects of goal directed fluid therapy based on dynamic parameters on post-surgical outcome: a meta-analysis of randomized controlled trials
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[Pubmed]  [Google Scholar] [DOI]
15 State-of-the-art fluid management in the operating room
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Best Practice & Research Clinical Anaesthesiology. 2014;
[Pubmed]  [Google Scholar] [DOI]
16 The Vigileo-FloTracTM System: Arterial Waveform Analysis for Measuring Cardiac Output and Predicting Fluid Responsiveness: A Clinical Review
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Journal of Cardiothoracic and Vascular Anesthesia. 2014;
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17 Venous oxygen saturation
Christiane Hartog,Frank Bloos
Best Practice & Research Clinical Anaesthesiology. 2014;
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18 A specialized post-anaesthetic care unit improves fast-track management in cardiac surgery: a prospective randomized trial
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Critical Care. 2014; 18(4): 468
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19 Impact of hemodynamic monitoring on clinical outcomes
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20 Improved Performance of the Fourth-Generation FloTrac/Vigileo System for Tracking Cardiac Output Changes
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Journal of Cardiothoracic and Vascular Anesthesia. 2014;
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21 Early goal-directed therapy based on endotracheal bioimpedance cardiography: a prospective, randomized controlled study in coronary surgery
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Journal of Clinical Monitoring and Computing. 2014;
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22 Update on clinical trials for the prevention of acute kidney injury in patients undergoing cardiac surgery
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American Journal of Surgery. 2013; 206(1): 86-95
[Pubmed]  [Google Scholar]
23 Goal-directed therapy in cardiac surgery: A systematic review and meta-analysis
Aya, H.D. and Cecconi, M. and Hamilton, M. and Rhodes, A. and Mahajan, R.P.
British Journal of Anaesthesia. 2013; 110(4): 510-517
[Pubmed]  [Google Scholar]
24 Echocardiography-Based Hemodynamic Management in the Cardiac Surgical Intensive Care Unit
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25 Goal-Directed Therapy in Cardiac Surgery: Are We There Yet?
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26 Perioperative increase in global blood flow to explicit defined goals and outcomes after surgery: a Cochrane Systematic Review
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27 Goal-directed therapy in cardiac surgery: a systematic review and meta-analysis
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[Pubmed]  [Google Scholar] [DOI]
28 Update on clinical trials for the prevention of acute kidney injury in patients undergoing cardiac surgery
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29 A systematic review of goal directed fluid therapy: Rating of evidence for goals and monitoring methods
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Journal of Critical Care. 2013;
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30 Algorithms: What Computers Do Best
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31 Guías de práctica clínica para el manejo del síndrome de bajo gasto cardíaco en el postoperatorio de cirugía cardíaca
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Medicina Intensiva. 2012; 36(4): e1
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32 Implementation of Molecular Phenotyping Approaches in the Personalized Surgical Patient Journey
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[Pubmed]  [Google Scholar] [DOI]
33 Clinical review: Goal-directed therapy-what is the evidence in surgical patients? The effect on different risk groups
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Critical Care. 2012; 17(2): 209
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34 Protocoled resuscitation and the prevention of acute kidney injury
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Current Opinion in Critical Care. 2012; 18(6): 613
[Pubmed]  [Google Scholar] [DOI]
35 Perioperative hemodynamic monitoring
Matthew E. Cove,Michael R. Pinsky
Best Practice & Research Clinical Anaesthesiology. 2012; 26(4): 453
[Pubmed]  [Google Scholar] [DOI]
36 Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review
John R Prowle,Horng-Ruey Chua,Sean M Bagshaw,Rinaldo Bellomo
Critical Care. 2012; 16(4): 230
[Pubmed]  [Google Scholar] [DOI]
37 Comparison of Goal-Directed Hemodynamic Optimization Using Pulmonary Artery Catheter and Transpulmonary Thermodilution in Combined Valve Repair: A Randomized Clinical Trial
Vsevolod V. Kuzkov, Konstantin V. Paromov, Andrey I. Lenkin, Mikhail Y. Kirov, Alexey A. Smetkin, Mons Lie, Lars J. Bjertnæs
Critical Care Research and Practice. 2012; 2012: 1
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38 Haemodynamic goal-directed therapy in cardiac and vascular surgery. A systematic review and meta-analysis
M. Giglio,L. Dalfino,F. Puntillo,G. Rubino,M. Marucci,N. Brienza
Interactive CardioVascular and Thoracic Surgery. 2012; 15(5): 878
[Pubmed]  [Google Scholar] [DOI]
39 Protocoled resuscitation and the prevention of acute kidney injury
Brienza, N. and Giglio, M.T. and Dalfino, L.
Current Opinion in Critical Care. 2012; 18(6): 613-622
[Pubmed]  [Google Scholar]
40 Perioperative hemodynamic monitoring
Cove, M.E. and Pinsky, M.R.
Best Practice and Research: Clinical Anaesthesiology. 2012; 26(4): 453-462
[Pubmed]  [Google Scholar]
41 Haemodynamic goal-directed therapy in cardiac and vascular surgery. A systematic review and meta-analysis
Giglio, M. and Dalfino, L. and Puntillo, F. and Rubino, G. and Marucci, M. and Brienza, N.
Interactive Cardiovascular and Thoracic Surgery. 2012; 15(5): 878-887
[Pubmed]  [Google Scholar]
42 Alternative Methods to Central Venous Pressure for Assessing Volume Status in Critically Ill Patients
Lisa Stoneking,Lawrence A. DeLuca,Albert B. Fiorello,Brendan Munzer,Nicola Baker,Kurt R. Denninghoff
Journal of Emergency Nursing. 2012;
[Pubmed]  [Google Scholar] [DOI]
43 Algorithms: What computers do best
Manecke Jr., G.R.
Journal of Cardiothoracic and Vascular Anesthesia. 2012; 26(5): 759-761
[Pubmed]  [Google Scholar]
44 Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review
Prowle, J.R. and Chua, H.-R. and Bagshaw, S.M. and Bellomo, R.
Critical Care. 2012; 16(4)
[Pubmed]  [Google Scholar]
45 Clinical practice guide for the management of low cardiac output syndrome in the postoperative period of heart surgery [Guías de práctica clínica para el manejo del síndrome de bajo gasto cardíaco en el postoperatorio de cirugía cardíaca]
Pérez Vela, J.L. and Martín Benítez, J.C. and Carrasco González, M. and De la Cal López, M.A. and Hinojosa Pérez, R. and Sagredo Meneses, V. and del Nogal Saez, F.
Medicina Intensiva. 2012; 36(4): e1-e44
[Pubmed]  [Google Scholar]
46 Implementation of molecular phenotyping approaches in the personalized surgical patient journey
Mirnezami, R. and Kinross, J.M. and Vorkas, P.A. and Goldin, R. and Holmes, E. and Nicholson, J. and Darzi, A.
Annals of Surgery. 2012; 255(5): 881-889
[Pubmed]  [Google Scholar]
47 Effects of advanced haemodynamic monitoring on perioperative outcome in high-risk patients [Hämodynamisches Monitoring - Verbessertes Outcome durch Erweitertes Perioperatives Hämodynamisches Monitoring]
Weyland, A. and Scheeren, T.
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie. 2012; 47(2): 92-99
[Pubmed]  [Google Scholar]
48 Haemodynamic changes after induction of anaesthesia with sevoflurane vs. propofol
PotoÄnik, I. and Janković, V.N. and Å tupnik, T. and Kremžar, B.
Signa Vitae. 2011; 6(2): 52-57
[Pubmed]  [Google Scholar]
49 Venous oximetry and the assessment of oxygen transport balance
Bronicki, R.A.
Pediatric Critical Care Medicine. 2011; 12(4 SUPPL.): S21-S26
[Pubmed]  [Google Scholar]
50 A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients
Hamilton, M.A. and Cecconi, M. and Rhodes, A.
Anesthesia and Analgesia. 2011; 112(6): 1392-1402
[Pubmed]  [Google Scholar]
51 Maintaining tissue perfusion in high-risk surgical patients: A systematic review of randomized clinical trials
Gurgel, S.T. and Do Nascimento Jr., P.
Anesthesia and Analgesia. 2011; 112(6): 1384-1391
[Pubmed]  [Google Scholar]
52 Comparison of continuous thoracic epidural with paravertebral block on perioperative analgesia and hemodynamic stability in patients having open lung surgery
Pintaric, T.S. and Potocnik, I. and Hadzic, A. and Stupnik, T. and Pintaric, M. and Jankovic, V.N.
Regional Anesthesia and Pain Medicine. 2011; 36(3): 256-260
[Pubmed]  [Google Scholar]
53 Pulse Pressure Variation Predicts Fluid Responsiveness in Elderly Patients After Coronary Artery Bypass Graft Surgery
Alexandre Yazigi, Eliane Khoury, Sani Hlais, Samia Madi-Jebara, Fadia Haddad, Gemma Hayek, Khalil Jabbour
Journal of Cardiothoracic and Vascular Anesthesia. 2011;
[HTML Full text]  [Google Scholar] [DOI]
54 Venous oximetry and the assessment of oxygen transport balance :
Ronald A. Bronicki
Pediatric Critical Care Medicine. 2011; 12: S21
[HTML Full text]  [Google Scholar] [DOI]
55 Relationship Between Plethysmographic Waveform Changes and Hemodynamic Variables in Anesthetized, Mechanically Ventilated Patients Undergoing Continuous Cardiac Output Monitoring
Robert H. Thiele, Douglas A. Colquhoun, James Patrie, Sarah H. Nie, Julie L. Huffmyer
Journal of Cardiothoracic and Vascular Anesthesia. 2011; 25(6): 1044
[HTML Full text]  [Google Scholar] [DOI]
56 Maintaining Tissue Perfusion in High-Risk Surgical Patients : A Systematic Review of Randomized Clinical Trials
Sanderland T. Gurgel, Paulo do Nascimento
Anesthesia & Analgesia. 2011; 112(6): 1384
[HTML Full text]  [Google Scholar] [DOI]
57 Patient blood management during cardiac surgery: Do we have enough evidence for clinical practice?
Journal of Thoracic and Cardiovascular Surgery. 2011;
[HTML Full text]  [Google Scholar] [DOI]
58 The relationship between inotrope exposure, six-hour postoperative physiological variables, hospital mortality and renal dysfunction in patients undergoing cardiac surgery
Jason Shahin, Benoit deVarennes, Chun Tse, Dan-Alexandru Amarica, Sandra Dial
Critical Care. 2011; 15(4): R162
[HTML Full text]  [Google Scholar] [DOI]
59 Comparison of Continuous Thoracic Epidural With Paravertebral Block on Perioperative Analgesia and Hemodynamic Stability in Patients Having Open Lung Surgery :
Tatjana Stopar Pintaric, Iztok Potocnik, Admir Hadzic, Tomaz Stupnik, Miha Pintaric, Vesna Novak Jankovic
Regional Anesthesia and Pain Medicine. 2011; 36(3): 256
[HTML Full text]  [Google Scholar] [DOI]
60 Stellenwert des perioperativen SzvO2-Monitorings
F. Bloos
Intensivmedizin und Notfallmedizin. 2010; 47(5): 338
[HTML Full text]  [Google Scholar] [DOI]
61 Perioperative haemodynamic therapy :
Hernandez, G., Peña, H., Cornejo, R., Rovegno, M., Retamal, J., Navarro, J.L., Aranguiz, I., (...), Bruhn, A. Mikhail Y Kirov, Vsevolod V Kuzkov, Zsolt Molnar
Current Opinion in Critical Care. 2010; 16(4): 384
[HTML Full text]  [Google Scholar] [DOI]
62 Contemporary Fluid Management in Cardiac Anesthesia
Marit Habicher, Albert Perrino, Claudia D. Spies, Christian von Heymann, Ulrike Wittkowski, Michael Sander
Journal of Cardiothoracic and Vascular Anesthesia. 2010;
[HTML Full text]  [Google Scholar] [DOI]
63 Perioperative haemodynamic therapy
Kirov, M.Y. and Kuzkov, V.V. and Molnar, Z.
Current Opinion in Critical Care. 2010; 16(4): 384-392
[Pubmed]  [Google Scholar]
64 Importance of perioperative ScvO2 monitoring [Stellenwert des perioperativen SzvO2-Monitorings]
Bloos, F.
Intensivmedizin und Notfallmedizin. 2010; 47(5): 338-344
[Pubmed]  [Google Scholar]
65 Clinical review: Goal-directed therapy in high risk surgical patients
Lees, N. and Hamilton, M. and Rhodes, A.
Critical Care. 2009; 13(5)
[Pubmed]  [Google Scholar]
66 Minimally invasive cardiac output monitoring in the perioperative setting
Funk, D.J. and Moretti, E.W. and Gan, T.J.
Anesthesia & Analgesia. 2009; 108(3): 887-897
[Pubmed]  [Google Scholar]
67 Does perioperative hemodynamic optimization protect renal function in surgical patients? A meta-analytic study.
Brienza, N. and Giglio, M.T. and Marucci, M. and Fiore, T.
Critical Care Medicine. 2009; 37(6): 2079-2090
[Pubmed]  [Google Scholar]
68 Minimally Invasive Cardiac Surgery
Hughes, J. and Piatt, K.
Cardiac Surgery Essentials for Critical Care Nursing. 2009; : 93
[Pubmed]  [Google Scholar]
69 Impact of emergency intubation on central venous oxygen saturation in critically ill patients: A multicenter observational study
Hernandez, G., Peña, H., Cornejo, R., Rovegno, M., Retamal, J., Navarro, J.L., Aranguiz, I., (...), Bruhn, A.
Critical Care. 2009; 13(3): R63
[Pubmed]  [Google Scholar]
70 Minimally Invasive Cardiac Output Monitoring in the Perioperative Setting
Duane J. Funk,Eugene W. Moretti,Tong J. Gan
Anesthesia & Analgesia. 2009; 108(3): 887
[Pubmed]  [Google Scholar] [DOI]
71 Does perioperative hemodynamic optimization protect renal function in surgical patients? A meta-analytic study
Nicola Brienza,Maria Teresa Giglio,Massimo Marucci,Tommaso Fiore
Critical Care Medicine. 2009; 37(6): 2079
[Pubmed]  [Google Scholar] [DOI]
72 Physiological changes of pregnancy and monitoring
Andrew Carlin,Zarko Alfirevic
Best Practice & Research Clinical Obstetrics & Gynaecology. 2008; 22(5): 801
[Pubmed]  [Google Scholar] [DOI]
73 Correlation between central venous oxygen saturation and oxygen delivery changes following fluid therapy : Correlation between ScvO2 and DO2
A. YAZIGI, H. ABOU-ZEID, S. MADI-JEBARA, F. HADDAD, G. HAYEK, K. JABBOUR
Acta Anaesthesiologica Scandinavica. 2008; 52(9): 1213
[HTML Full text]  [Google Scholar] [DOI]
74 Using ventilation-induced plethysmographic variations to optimize patient fluid status
Desebbe, O., Cannesson, M.
Current Opinion in Anaesthesiology. 2008; 21(6): 772-778
[Pubmed]  [Google Scholar]
75 Using ventilation-induced plethysmographic variations to optimize patient fluid status
Olivier Desebbe,Maxime Cannesson
Current Opinion in Anaesthesiology. 2008; 21(6): 772
[Pubmed]  [Google Scholar] [DOI]
76 Correlation between central venous oxygen saturation and oxygen delivery changes following fluid therapy
Yazigi, A. and Abou-Zeid, H. and Madi-Jebara, S. and Haddad, F. and Hayek, G. and Jabbour, K.
Acta Anaesthesiologica Scandinavica. 2008; 52(9): 1213-1217
[Pubmed]  [Google Scholar]
77 Physiological changes of pregnancy and monitoring
Carlin, A. and Alfirevic, Z.
Best Practice & Research Clinical Obstetrics & Gynaecology. 2008; 22(5): 801-823
[Pubmed]  [Google Scholar]
78 Cardiac output--have we found theægold standardæ?
Chakravarthy, M.
Annals of cardiac anaesthesia. ; 11(1): 1
[Pubmed]  [Google Scholar]

 
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