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Successful medical management of fungal infective endocarditis post VSD closure


1 Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India
2 Department of CTVS, PGIMER, Chandigarh, India

Correspondence Address:
Banashree Mandal
Room Number 4015, 4th Floor, Advanced Cardiac Centre, PGIMER, Sector 12, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aca.ACA_33_19

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Year : 2021  |  Volume : 24  |  Issue : 1  |  Page : 95-98

 

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Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3'–6.8' of all IE cases and is considered the most severe form with a mortality rate as high as 45'–50'. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100' without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B.






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1 Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India
2 Department of CTVS, PGIMER, Chandigarh, India

Correspondence Address:
Banashree Mandal
Room Number 4015, 4th Floor, Advanced Cardiac Centre, PGIMER, Sector 12, Chandigarh - 160 012
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aca.ACA_33_19

Rights and Permissions

Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3'–6.8' of all IE cases and is considered the most severe form with a mortality rate as high as 45'–50'. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100' without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B.






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