Next article Search Articles Instructions for authors  Access Statistics | Citation Manager  
CASE REPORT  

 Article Access Statistics
    Viewed5242    
    Printed205    
    Emailed3    
    PDF Downloaded401    
    Comments [Add]    
    Cited by others 11    

Recommend this journal


Click on image for details.

 Dexmedetomidine controls junctional ectopic tachycardia during Tetralogy of Fallot repair in an infant

Michelle LeRiger1, Aymen Naguib1, Mark Gallantowicz2, Joseph D Tobias3
1 Department of Anesthesiology, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA
2 Department of Cardiothoracic Surgery and The Heart Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA
3 Department of Anesthesiology and Pediatrics, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA

Correspondence Address:
Michelle LeRiger
Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-9784.97978

Rights and Permissions

Year : 2012  |  Volume : 15  |  Issue : 3  |  Page : 224-228

 
SEARCH
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles

  Article in PDF (328 KB)
Email article
Print Article
Add to My List
Dexmedetomidine is a highly selective α2 -adrenergic agonist approved for short-term sedation and monitored anesthesia care in adults. Although not approved for use in the pediatric population, an increasing number of reports describe its use in pediatric patients during the intraoperative period and in the intensive care unit. Dexmedetomidine can potentially have an adverse impact on the cardiovascular system secondary to its negative chronotropic and dromotropic effects. However, it is these cardiac effects that are currently being explored as a therapeutic option for the treatment of perioperative tachyarrhythmias in pediatric patients with congenital heart disease (CHD). We report the use of dexmedetomidine to treat junctional ectopic tachycardia (JET), which developed following cardiopulmonary bypass for surgical correction of Tetralogy of Fallot in a 6-week-old infant. Within 15 min of increasing the dexmedetomidine infusion from 0.5 to 3 μg/kg/h, JET converted to normal sinus rhythm. This case report provides additional anecdotal evidence that dexmedetomidine may have a therapeutic role in the treatment of perioperative tachyarrhythmias in pediatric patients with CHD. The specific effects of dexmedetomidine on the cardiac conduction system are reviewed followed by a summary of previous reports describing its use as a therapeutic agent to treat perioperative arrhythmias.






[FULL TEXT] [PDF]*
 

 

  Sitemap | Feedback | Disclaimer | What's New |  
  © Annals of Cardiac Anaesthesia | Published by Wolters Kluwer - Medknow
 Online since 5th January, 2008

 

 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 
 
 Reader Comments
 Email Alert *
  *
 * Requires registration (Free)
 
 CASE REPORT
 



Michelle LeRiger1, Aymen Naguib1, Mark Gallantowicz2, Joseph D Tobias3
1 Department of Anesthesiology, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA
2 Department of Cardiothoracic Surgery and The Heart Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA
3 Department of Anesthesiology and Pediatrics, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105, USA

Correspondence Address:
Michelle LeRiger
Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43105
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-9784.97978

Rights and Permissions

Dexmedetomidine is a highly selective α2 -adrenergic agonist approved for short-term sedation and monitored anesthesia care in adults. Although not approved for use in the pediatric population, an increasing number of reports describe its use in pediatric patients during the intraoperative period and in the intensive care unit. Dexmedetomidine can potentially have an adverse impact on the cardiovascular system secondary to its negative chronotropic and dromotropic effects. However, it is these cardiac effects that are currently being explored as a therapeutic option for the treatment of perioperative tachyarrhythmias in pediatric patients with congenital heart disease (CHD). We report the use of dexmedetomidine to treat junctional ectopic tachycardia (JET), which developed following cardiopulmonary bypass for surgical correction of Tetralogy of Fallot in a 6-week-old infant. Within 15 min of increasing the dexmedetomidine infusion from 0.5 to 3 μg/kg/h, JET converted to normal sinus rhythm. This case report provides additional anecdotal evidence that dexmedetomidine may have a therapeutic role in the treatment of perioperative tachyarrhythmias in pediatric patients with CHD. The specific effects of dexmedetomidine on the cardiac conduction system are reviewed followed by a summary of previous reports describing its use as a therapeutic agent to treat perioperative arrhythmias.






[FULL TEXT] [PDF]*


        
Print this article     Email this article  

  Sitemap | Feedback | Disclaimer | What's New |  
  © Annals of Cardiac Anaesthesia | Published by Wolters Kluwer - Medknow
 Online since 5th January, 2008