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LETTER TO EDITOR Table of Contents   
Year : 2010  |  Volume : 13  |  Issue : 1  |  Page : 74
hs-CRP as a predictive factor for cardiac outcome

Wiwanitkit House, Bangkhae, Bangkok-10160, Thailand

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Date of Web Publication11-Jan-2010

How to cite this article:
Wiwanitkit V. hs-CRP as a predictive factor for cardiac outcome. Ann Card Anaesth 2010;13:74

How to cite this URL:
Wiwanitkit V. hs-CRP as a predictive factor for cardiac outcome. Ann Card Anaesth [serial online] 2010 [cited 2022 Dec 8];13:74. Available from:

The Editor,

I read the report on evaluation on high-sensitivity C-reactive protein (hs-CRP) by Balciunus et al., with a great interest. [1] Balciunus et al., reported that preoperative inflammatory state, as measured by hs-CRP, is an important determinant of postoperative outcome after coronary artery bypass graft (CABG) surgery. [1] I agree with the Balciunus et al., that hs-CRP has predictive value of scores in cardiac surgery. Indeed, this finding is correct and can be predicted. In laboratory medicine, hs-CRP is accepted as a good laboratory test for cardiac pathology, [2] not only for the scenario of postcardiac surgery; basically, CRP is useful in predicting early, intermediate-term, and long-term mortality and major adverse cardiac events in patients undergoing vascular surgeries. The new generation of the test, with higher sensitivity, hs-CRP has a more usefulness in this purpose. [3] Low et al., recently said that "hs-CRP is useful in further stratifying high-risk multi-ethnic patients presenting with chest pain despite no evidence of myocardial infarction". [3] In addition, Ucar et al., noted that hs-CRP has a good utility in prediction of atrial fibrillation after bypass surgery. [4] However, the difference in hs-CRP levels before the bypass grafting surgery due to the difference underlying pathological conditions should be mentioned. The recent study by Shakouri et al., showed that the patients undergoing cardiac bypass surgery with common carotid artery stenosis had higher levels of serum hs-CRP than patients without stenosis. [5]

   References Top

1.Balciunas M, Bagdonaite L, Samalavicius R, Griskevicius L, Vuylsteke A. Pre-operative high sensitive C-reactive protein predicts cardiovascular events after coronary artery bypass grafting surgery: A prospective observational study. Ann Card Anaesth 2009;12:127-32.   Back to cited text no. 1  [PUBMED]  Medknow Journal  
2.Corrado E, Novo S. High sensitivity of C-reactive protein in primary prevention. G Ital Cardiol (Rome) 2007;8:327-34.  Back to cited text no. 2  [PUBMED]    
3.Low AF, Seow SC, Yeoh KG, Lim YT, Tan HC, Yeo TC. High-sensitivity C-reactive protein is predictive of medium-term cardiac outcome in high-risk Asian patients presenting with chest pain syndrome without myocardial infarction. Ann Acad Med Singapore 2004;33:407-12.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]  
4.Ucar HI, Tok M, Atalar E, Dogan OF, Oc M, Farsak B, et al. Predictive significance of plasma levels of interleukin-6 and high-sensitivity C-reactive protein in atrial fibrillation after coronary artery bypass surgery. Heart Surg Forum 2007;10:E131-5.  Back to cited text no. 4  [PUBMED]  [FULLTEXT]  
5.Shakouri P, Nezami N, Tarzamni MK, Rashid RJ. The elusive link between high sensitivity C-reactive protein and carotid subclinical atherosclerosis in coronary artery bypass grafting candidates: A cross-sectional study. Cardiovasc Ultrasound 2008;6:23.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]  

Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok-10160
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-9784.58844

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