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Figure 1: (a) Receiver operating characteristic curve for lactate (T3), (b) receiver operating characteristic curve for base excess (T3) (c) Receiver operating characteristic curve for oxygen partial pressure. (a - c) Receiver operating characteristic curves at T3 time point for lactate, base excess, and oxygen partial pressure. The lactate levels (T3) showed highest mortality predictive value with an area under curve of 96.9% (sensitivity: 90.9%, specificity: 89.9%, and cutoff value ≥3.0 mmol/l). The mortality predictive value of base excess (T3) was close to lactate with an area under curve of 94.5% (sensitivity: 89.9%, specificity: 90.9%, and cutoff value ≤3.25), while oxygen partial pressure (T3) showed lowest mortality predictive value out of the three biomarkers with an area under curve of 81.1% (sensitivity: 72.7%, specificity: 72.7%, and cutoff value ≤ 66.1 mmHg)

Figure 1: (a) Receiver operating characteristic curve for lactate (T3), (b) receiver operating characteristic curve for base excess (T3) (c) Receiver operating characteristic curve for oxygen partial pressure. (a - c) Receiver operating characteristic curves at T3 time point for lactate, base excess, and oxygen partial pressure. The lactate levels (T3) showed highest mortality predictive value with an area under curve of 96.9% (sensitivity: 90.9%, specificity: 89.9%, and cutoff value ≥3.0 mmol/l). The mortality predictive value of base excess (T3) was close to lactate with an area under curve of 94.5% (sensitivity: 89.9%, specificity: 90.9%, and cutoff value ≤3.25), while oxygen partial pressure (T3) showed lowest mortality predictive value out of the three biomarkers with an area under curve of 81.1% (sensitivity: 72.7%, specificity: 72.7%, and cutoff value ≤ 66.1 mmHg)