ACA App
Annals of Cardiac Anaesthesia Annals of Cardiac Anaesthesia Annals of Cardiac Anaesthesia
Home | About us | Editorial Board | Search | Ahead of print | Current Issue | Archives | Submission | Subscribe | Advertise | Contact | Reader Login
Users online: 1128 Small font size Default font size Increase font size Print this article Email this article Bookmark this page
  Instructions 
  Search 
  My preferences 

 


Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Access statistics : Table of Contents
   2004| January  | Volume 7 | Issue 1  
    Online since January 22, 2008

 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Viewed PDF Cited
ORIGINAL ARTICLES
A Comparison of aminocaproic Acid and Tranexamic Acid in Adult Cardiac Surgery.
S Chauhan, P Gharde, A Bisoi, S Kale, U Kiran
January 2004, 7(1):40-3
PMID:17827560
We compared Aminocaproic acid with tranexamic acid, prospectively in 120 patients undergoing coronary artery bypass surgery on cardiopulmonary bypass. Patients were assigned to one of the 3 groups. Group A (n=40) did not receive any drug and acted as the control group. Group B (n=4) received aminocaproic acid 100 mg/kg each at anaesthetic induction, on bypass and after protamine reversal of heparin. group C (n=40) received tranexamic acid 10 mg/kg each at anaesthetic induction, on bypass and after protamine reversal of heparin. Postoperative blood loss at 24 hours, blood and blood product usage, and re-exploration rates were recorded, and tests for coagulation were performed at 6 hours postoperatively. It was found that blood loss in group A at 24 hours (780+/-120 mL) was significantly greater than Group B (360+/-90 mL) and Group C (215+/-70 mL). Plasma and platelet concentrate use in Group A (215+/-30 mL and 150+/-30 mL) was greater than Group B (190+/-20 mL and 75+/-30 mL) and Group C (185+/-20 mL and 80+/-30 mL). Re- explorations in Group A, 8/40 (20%) were greater than Group B, 2/40 (5%) and Group C, 2/40 (5%). Coagulation tests revealed better preservation of fibrinogen and lower levels of fibrin degradation products, in group B and C. These two groups were however statistically indistinguishable in respect to all the parameters studied, when compared with each other. It was concluded that both the antifibrinolytic agents in the doses studied were equally effective in reducing postoperative blood loss, blood and blood products usage and re-exploration rates. Coagulation parameters were better preserved as compared to the control group.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  1,709 492 -
Comparative study of pulsatile and nonpulsatile flow during cardio-pulmonary bypass.
P Poswal, Y Mehta, R Juneja, S Khanna, Zile Singh Meharwal, N Trehan
January 2004, 7(1):44-50
PMID:17827561
The use of nonpulsatile flow during extracorporeal circulation remains popular despite theoretical advantages of pulsatile cardiopulmonary bypass (CPB). Pulsatile CPB is considered to be more physiological than nonpulsatile flow as the pulsatile energy ensures the patency of the vascular bed and mechanical motion of tissue fluid around the cell membrane, improves microcirculation and enhances diffusion. The purpose of this study was to compare the effect of pulsatile and nonpulsatile flow on the coagulation profile, liver and kidney function and also on the haemodynamics in patients undergoing coronary artery bypass grafting on CPB. One hundred patients between 35 and 65 years of age with normal left ventricular function were randomly divided into two equal groups: Pulsatile (P) and nonpulsatile (NP). Haematological parameters, clotting profile, renal parameters, hepatic function tests and haemodynamic variables were measured preoperatively and postoperatively at specific intervals. Surgical, anaesthetic and CPB regimen was standard in all cases. There was a decrease in platelet count during and after CPB in both groups. Coagulation profile and renal function parameters remained similar in both groups except that creatinine clearance was better in group P on the first postoperative day. Urine output was also better in group P. There was no change in liver function tests in both groups. The haemodynamic variables were comparable in both groups. The systemic vascular resistance was higher in group NP postoperatively and oxygen consumption was higher in group P post CPB. In conclusion we did not find any significant difference between pulsatile and nonpulsatile flow during CPB except the creatinine clearance and urine output were better in pulsatile group.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  1,535 419 -
Influence of isoflurane on ischaemic heart disease in patients with coronary steal prone anatomy.
C Murugesan, K Murthy, R Garg, S Kumar, K Muralidhar
January 2004, 7(1):51-4
PMID:17827562
It is postulated that patients with ischaemic heart disease (IHD) and coronary steal prone anatomy (CSPA) may develop myocardial ischaemia under isoflurane anaesthesia. This study was conducted in 50 patients undergoing coronary artery bypass grafting. Among these 10 patients (20%) had CSPA, as evidenced by coronary angiography. Anaesthesia was induced with fentanyl, midazolam and thiopentone and maintained with isoflurane in oxygen after endotracheal intubation. Patients were continuously monitored with automated ST segment analysis of electrocardiogram (ECG) and transoesophageal echocardiography (TEE). The end-tidal concentration of isoflurane was maintained at 1.2%, which is equal to one minimum alveolar concentration. Haemodynamic parameters were maintained within 20% of baseline values with either the use of phenylephrine or increasing the depth of anaesthesia by using midazolam and fentanyl. ST changes were measured after 80 ms of J-point in ECG and TEE monitored for occurrence of new regional wall motion abnormalities during the study period. ST changes more than +/-1.0 mm were considered as an indication of myocardial ischaemia. Out of 10 patients having CSPA, 50% developed significant ECG changes during isoflurane anaesthesia at an endtidal concentration of 1.2%. In patients not having CSPA new ischaemia was not observed. Our study indicates necessity of close monitoring of patients with IHD and CSPA during isoflurane anaesthesia to identify new ischaemia and institute appropriate measures.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  1,304 265 -
REVIEW ARTICLES
The incidence and pathogenesis of acute renal failure following cardiac surgery, and strategies for its prevention.
Katherine G Yallop, David C Smith
January 2004, 7(1):17-31
PMID:17827558
Renal dysfunction following cardiopulmonary bypass (CPB) causes significant morbidity and mortality. There has been much research into possible methods of reducing renal damage, but much promising laboratory work has failed to live up to expectations in the clinical arena, such that there is no widely accepted renal protection strategy for cardiac surgical patients. Part of the difficulty is that there is no standardized definition of renal dysfunction, and there are a limited number of good quality randomised controlled clinical trials.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  961 357 -
CASE REPORTS
Pulmonary hypertensive crisis following ventricular septal defect closure in a 12 year old child.
OP Sanjay, P Prashanth
January 2004, 7(1):59-61
PMID:17827564
Full text not available  [PDF]  [PubMed]
  807 249 -
REVIEW ARTICLES
Anaesthesia for procedures in cardiac catheterisation laboratory.
S Goel, Deepak K Tempe
January 2004, 7(1):32-9
PMID:17827559
Full text not available  [PDF]  [PubMed]
  586 341 -
EDITORIAL
Growing responsibilities of a cardiac anaesthesiologist.
Deepak K Tempe
January 2004, 7(1):15-6
PMID:17827557
Full text not available  [PDF]  [PubMed]
  703 180 -
CASE REPORTS
Deep neck abscess - a rare encounter during internal jugular vein cannulation.
A Pai, S Ghaste
January 2004, 7(1):67-8
PMID:17827566
Full text not available  [PDF]  [PubMed]
  616 254 -
TUTORIAL
Percutaneous dilational tracheostomy.
Sushil P Ambesh, Justiaan Lc Swanevelder
January 2004, 7(1):77-85
PMID:17827569
Full text not available     [PubMed]
  596 0 -
CASE REPORTS
Anaesthesia for Total Endoscopic CABG - A Case Report.
Y Mehta, A Gupta, KK Sharma, Y Mishra, Mitesh B Sharma, Harpreet S Wasir, N Trehan
January 2004, 7(1):55-8
PMID:17827563
Full text not available     [PubMed]
  561 0 -
INTERESTING IMAGES
Antero-apical left ventricular aneurysm with thrombus.
P Vaijyanath, B Mishra, S Khanna, S Verghese
January 2004, 7(1):75-75
PMID:17827567
Full text not available     [PubMed]
  467 0 -
CASE REPORTS
Atrial septostomy for acute right ventricular failure following mitral valve replacement - a case report.
V Datt, Deepak K Tempe, MA Geelani, AS Tomar, S Virmani, M Goel, N Kaushik
January 2004, 7(1):62-6
PMID:17827565
Full text not available     [PubMed]
  411 0 -
INTERESTING IMAGES
Firefighters' boot : angiocardiographic appearance of an unruptured aneurysm of the sinus of valsalva.
Vithal Kumar Betigeri, A Banerjee, V Sharma, A Nagesh, K Satya Sreedhar, Vijay K Trehan
January 2004, 7(1):76-76
PMID:17827568
Full text not available     [PubMed]
  381 0 -