Year : 2019  |  Volume : 22  |  Issue : 3  |  Page : 254--259

Furosemide: Would it help to improve the lungs as evaluated by sonography and compliance during aortic coarctation surgery


Ahmed Kareem Mohammed1, Mai A Madkour1, Hossam M Hassanien2 
1 Department of Anesthesia, Surgical Intensive Care and Pain Management, Faculty of Medicine, Cairo University, Cairo, Egypt
2 Department of Cardiothoracic Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Ahmed Kareem Mohammed
Department of Anesthesia, Surgical Intensive Care and Pain Management, Faculty of Medicine, Cairo University, Kasr Al Aini, Cairo
Egypt

Background: We evaluated furosemide on attenuating lung injury and/or edema during coarctation repair surgery. We evaluated dynamic lung compliance. We measured the degree of lung edema by means of lung ultrasound (LUS). We recorded the (PaO2/FiO2ratio) as an indicator for oxygenation. Materials and Methods: A study was conducted on 56 patients. Patients were divided into two groups: control group (Group C) which did not receive furosemide and furosemide group (Group F) at a dose of 1 mg/kg at induction of anesthesia. Dynamic lung compliance was calculated at induction (Cdyn 1) and at the end of the surgery (Cdyn 2). The (PaO2/FiO2ratio) was calculated at start and end of surgery as (PF 1) and (PF 2), respectively. LUS was performed after induction (LUS 1) and at the end of the surgery. LUS 2 using the 12 regions method plotting the results on scale from 0 to 36. Mechanical ventilation days were recorded. Results: Administering furosemide attenuated the lung injury/edema and other pulmonary complications. Furosemide administration improved the dynamic lung compliance in the F Group compared to the C Group. Furthermore, it increased the (PaO2/FiO2ratio) in the F Group compared to the C Group. LUS scale values were lower in the F Group compared to the C Group. There was also less postoperative mechanical ventilation days. Conclusions: The use of furosemide was accompanied by improved lung injury/edema profile as indicated by a much less drop in dynamic lung compliance, better oxygenation, a more favorable LUS scale with less parenchymal lung affection.


How to cite this article:
Mohammed AK, Madkour MA, Hassanien HM. Furosemide: Would it help to improve the lungs as evaluated by sonography and compliance during aortic coarctation surgery.Ann Card Anaesth 2019;22:254-259


How to cite this URL:
Mohammed AK, Madkour MA, Hassanien HM. Furosemide: Would it help to improve the lungs as evaluated by sonography and compliance during aortic coarctation surgery. Ann Card Anaesth [serial online] 2019 [cited 2019 Sep 19 ];22:254-259
Available from: http://www.annals.in/article.asp?issn=0971-9784;year=2019;volume=22;issue=3;spage=254;epage=259;aulast=Mohammed;type=0