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Annals of Cardiac Anaesthesia Annals of Cardiac Anaesthesia Annals of Cardiac Anaesthesia
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VIDEO COMMENTARY 2  
Year : 2017  |  Volume : 20  |  Issue : 1  |  Page : 122
Effect of heparin and Bivalirudin on the kinetics of clot formation: Viscoelastic coagulation testing


Department of Cardiac Anaesthesiology, Cardio Thoracic Centre, All India Institute of Medical Sciences, New Delhi, India

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Date of Web Publication6-Jan-2017
 

How to cite this article:
Hasija S, Kapoor PM. Effect of heparin and Bivalirudin on the kinetics of clot formation: Viscoelastic coagulation testing. Ann Card Anaesth 2017;20:122

How to cite this URL:
Hasija S, Kapoor PM. Effect of heparin and Bivalirudin on the kinetics of clot formation: Viscoelastic coagulation testing. Ann Card Anaesth [serial online] 2017 [cited 2020 Jul 5];20:122. Available from: http://www.annals.in/text.asp?2017/20/1/122/197855



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Heparin is a widely used anticoagulant that inhibits thrombin and factor Xa via antithrombin III. Bivalirudin is a direct thrombin inhibitor and does not inhibit factor Xa. It inhibits both circulating and clot-bound thrombin. In order to better understand the mechanisms of action of these anticoagulants, we studied their effects on the viscoelastic coagulation tests: Rotational thromboelastometry, Thromboelastography and Sonoclot.Here, we provide only representative signatures obtained on viscoelastic coagulation testing of blood samples of patients undergoing open heart surgery and anticoagulated with either heparin or bivalirudin.







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Correspondence Address:
Poonam Malhotra Kapoor
Professor, Cardiac Anaesthesia, CTC, AIIMS, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-9784.197855

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